RESUMO
No disponible
Assuntos
Humanos , Masculino , História do Século XX , Guerra do Vietnã , Oftalmologia/história , Oftalmologia , Oftalmopatias/história , Oftalmopatias/prevenção & controle , Traumatismos Oculares/complicações , Traumatismos Oculares/história , Traumatismos Oculares/prevenção & controle , Dispositivos de Proteção dos Olhos/história , Dispositivos de Proteção dos Olhos/tendências , Dispositivos de Proteção dos Olhos , Corpos Estranhos/história , Corpos Estranhos/cirurgiaRESUMO
No disponible
Assuntos
Humanos , Masculino , Feminino , Atenção à Saúde/história , Atenção à Saúde , Atenção à Saúde/organização & administração , Atenção à Saúde/legislação & jurisprudência , Atenção à Saúde/tendênciasAssuntos
Cegueira/história , Leitura , Auxiliares Sensoriais/história , Brasil , França , História do Século XIX , Humanos , Moldávia , Filatelia , Federação RussaAssuntos
Cegueira/história , Pessoas Famosas , Medicina nas Artes , Pinturas/história , Cura pela Fé/história , Grécia , História do Século XVI , Humanos , EspanhaAssuntos
Cegueira/história , Medicina nas Artes , Música/história , Pinturas/história , França , História do Século XVI , Humanos , MasculinoRESUMO
No disponible
Assuntos
Humanos , Masculino , Feminino , História do Século XX , Oftalmologia/história , Oftalmologia/métodos , Oftalmologia/normas , Oftalmopatias/diagnóstico , Oftalmopatias/genética , Oftalmopatias/classificação , Oftalmopatias/congênito , Oftalmopatias/complicações , Oftalmopatias/cirurgia , I Guerra MundialRESUMO
CASO CLÍNICO: Se expone el caso de dos hermanos que presentaron neovascularización coroidea asociada a estrías angioides. Ambos pacientes fueron tratados con una inyección mensual de ranibizumab (Lucentis®) intravítrea durante tres meses. La visión se estabilizó y la angiografía fluoresceínica mostró resolución completa de la neovascularización coroidea. Durante el seguimiento, no observamos recurrencia del cuadro. DISCUSIÓN: El uso de ranibizumab intravítreo en caso de neovascularización coroidea asociada a estrías angioides ha mostrado resultados favorables. No obstante, serán necesarias series de casos mayores que nos permitan conocer la verdadera eficacia de este tratamiento
CASE REPORT: We report a familial case of 2 brothers that suffered choroidal neovascularization (CNV) secondary to angioid streaks. They were both treated with a monthly intravitreal injection of ranibizumab (Lucentis®) for 3 months. Visual acuity was stabilized and fluorescein angiography revealed complete resolution of CNV. Neither recurrent CNV lesion nor new hemorrhages were reported during the follow-up period. Discussion: The use of intravitreal ranibizumab for the treatment of CNV in patients with angioid streaks has shown favorable results. However, further studies with a longer follow-up and larger number of patients are necessary to more precisely determine the results of this therapy
Assuntos
Humanos , Masculino , Neovascularização de Coroide/etiologia , Estrias Angioides/complicações , Anticorpos Monoclonais/administração & dosagem , Pseudoxantoma Elástico/diagnósticoRESUMO
CASE REPORT: We report a familial case of 2 brothers that suffered choroidal neovascularization (CNV) secondary to angioid streaks. They were both treated with a monthly intravitreal injection of ranibizumab (Lucentis(®)) for 3 months. Visual acuity was stabilized and fluorescein angiography revealed complete resolution of CNV. Neither recurrent CNV lesion nor new hemorrhages were reported during the follow-up period. DISCUSSION: The use of intravitreal ranibizumab for the treatment of CNV in patients with angioid streaks has shown favorable results. However, further studies with a longer follow-up and larger number of patients are necessary to more precisely determine the results of this therapy.
Assuntos
Estrias Angioides/complicações , Neovascularização de Coroide/etiologia , Estrias Angioides/genética , Neovascularização de Coroide/genética , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
OBJECTIVE: To investigate the changes induced by a pterygium or its surgical removal on the biomechanical properties of the cornea and to determine factors that might affect these parameters. METHODS: This prospective pilot interventional, non-randomized, observer-masked study included 20 eyes of 20 patients with a unilateral primary pterygium (pterygium group) and 19 fellow healthy eyes (control group). The bare sclera technique with one-minute application of 0.02% mitomycin C intraoperatively was performed in all cases. The follow-up period was one month. The preoperative and postoperative biomechanical properties of the cornea were measured using the Reichert ocular response analyzer (ORA). RESULTS: The corneal hysteresis (CH) decreased significantly (P<.01) in eyes with a pterygium compared to the control eyes, while surgery did not significantly change the CH compared to preoperatively. There were no significant changes in the corneal resistance factor or the central corneal thickness. CONCLUSIONS: Primary active pterygium (grades 1 or 2) induce a reduction of corneal biomechanical features. Further studies are needed in populations, with longer follow-ups and bigger pterygium that may involve wider keratectomy to confirm our results.
Assuntos
Córnea/fisiopatologia , Pterígio/fisiopatologia , Adulto , Idoso , Fenômenos Biomecânicos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Estudos Prospectivos , Pterígio/cirurgiaRESUMO
Objetivo: Investigar los cambios inducidos en la biomecánica de la córnea por la presencia de pterigión o por su exéresis quirúrgica, así como determinar los factores que influyen sobre dichos parámetros. Métodos: Estudio piloto, intervencional y prospectivo, con observador enmascarado que incluía 20 ojos de 20 pacientes con pterigión primario unilateral (grupo pterigión) y 19 ojos adelfos sanos (grupo control). Se realizó una resección simple del pterigión con aplicación intraoperatoria de mitomicina C 0,02% durante un minuto sobre el lecho escleral. El periodo de seguimiento fue de un mes. Las propiedades biomecánicas de la córnea fueron determinadas preoperatoria y postoperatoriamente mediante el analizador de respuesta ocular Reichert (ORA). Resultados: La presencia de pterigión disminuyó significativamente la histéresis corneal (HC) en comparación con el grupo control (p<0,01). No encontramos diferencias estadísticamente significativas entre las medidas pre- y postoperatorias de la HC, del factor de resistencia corneal, ni del espesor corneal central. Conclusión: La presencia de un pterigión primario activo (grados 1 y 2) conduce a una reducción de las propiedades biomecánicas de la córnea. Serían necesarios nuevos estudios con un mayor tiempo de seguimiento y pterigiones más avanzados, con queratectomías más amplias para confirmar estos efectos(AU)
Objective: To investigate the changes induced by a pterygium or its surgical removal on the biomechanical properties of the cornea and to determine factors that might affect these parameters. Methods: This prospective pilot interventional, non-randomized, observer-masked study included 20 eyes of 20 patients with a unilateral primary pterygium (pterygium group) and 19 fellow healthy eyes (control group). The bare sclera technique with one-minute application of 0.02% mitomycin C intraoperatively was performed in all cases. The follow-up period was one month. The preoperative and postoperative biomechanical properties of the cornea were measured using the Reichert ocular response analyzer (ORA). Results: The corneal hysteresis (CH) decreased significantly (P<0.01) in eyes with a pterygium compared to the control eyes, while surgery did not significantly change the CH compared to preoperatively. There were no significant changes in the corneal resistance factor or the central corneal thickness. Conclusions: Primary active pterygium (grades 1 or 2) induce a reduction of corneal biomechanical features. Further studies are needed in populations, with longer follow-ups and bigger pterygium that may involve wider keratectomy to confirm our results(AU)
Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Pterígio/diagnóstico , Pterígio/tratamento farmacológico , Pterígio/cirurgia , Fenômenos Biomecânicos , Fenômenos Biomecânicos/fisiologia , Mitomicina/uso terapêutico , Procedimentos Cirúrgicos Oftalmológicos/métodos , Pterígio/fisiopatologia , Pterígio , Mitomicina/metabolismo , Mitomicina/farmacocinética , Estudos Prospectivos , Análise de Variância , Ceratectomia FotorrefrativaRESUMO
CASE REPORT: An 83 year-old male reported to the emergency room with red eye and ocular pain. The slit-lamp examination showed a central corneal perforation of 1mm in diameter, with no associated infection or inflammatory process. The patient had no history of trauma. It was decided to apply a patch of Tachosil(®) at the site of corneal perforation. After 36 hours of occlusion, a layer of fibrin covered the perforation, closing the defect. Successful healing of the corneal perforation was observed in the follow-up, with no recurrences of the process. CONCLUSIONS: Tachosil(®) is collagen sponge with human fibrin and human thrombin used in cardiological and neurosurgical surgery for haemostasis and the occlusion of vessels and meninges. We present the first indication in ophthalmology of Tachosil(®) as an effective alternative in the treatment of sterile non-traumatic corneal perforations less than 1.5 mm in size.
Assuntos
Implantes Absorvíveis , Perfuração da Córnea/terapia , Fibrinogênio/uso terapêutico , Tampões de Gaze Cirúrgicos , Trombina/uso terapêutico , Idoso de 80 Anos ou mais , Doença de Alzheimer/complicações , Antibioticoprofilaxia , Lentes de Contato , Perfuração da Córnea/etiologia , Úlcera da Córnea/complicações , Combinação de Medicamentos , Humanos , Masculino , Medroxiprogesterona/uso terapêutico , Midriáticos/uso terapêuticoRESUMO
Caso clínico: Varón de 83 años que acude a urgencias por dolor ocular en ojo derecho y enrojecimiento.En la exploración se objetivó una lesión perforante corneal central de 1mm dediámetro sin proceso infeccioso o inflamatorio concomitante ni antecedentes traumáticos.Procedimos al cierre urgente del defecto, aplicando un parche de Tachosil® sobre la zonaperforada. Tras 36 horas de oclusión un material fibrinoide ocluía la perforación cerrandoel defecto. En el posterior seguimiento no se presentaron recurrencias ni efectos adversospersistiendo el sellado completo del defecto.Conclusiones: Tachosil® es una esponja colágena de fibrinógeno y trombina humanos utilizadapara favorecer la hemostasia y la reparación tisular en cirugías cardíacas, urológicasy neuroquirúrgicas. Presentamos la primera indicación oftalmológica de Tachosil® comouna posible alternativa efectiva y de fácil uso en las perforaciones corneales no traumáticasestériles menores de 1,5mm(AU)
Case report: An 83 year-old male reported to the emergency room with red eye and ocularpain. The slit-lamp examination showed a central corneal perforation of 1mm in diameter,with no associated infection or inflammatory process. The patient had no history of trauma.It was decided to apply a patch of Tachosil® at the site of corneal perforation. After 36 hoursof occlusion, a layer of fibrin covered the perforation, closing the defect. Successful healingof the corneal perforationwas observed in the follow-up, with no recurrences of the process.Conclusions: Tachosil® is collagen sponge with human fibrin and human thrombin used incardiological and neurosurgical surgery for haemostasis and the occlusion of vessels andmeninges. We present the first indication in ophthalmology of Tachosil® as an effectivealternative in the treatment of sterile non-traumatic corneal perforations less than 1.5mmin size(AU)
